Sophia Bush, Adrian Grenier get awkward for cancer awareness

We've all had the awkward sex talk with our parents. (If yours wasn't awkward, go give your parents a hug right now, because they're obviously magical.) Now, a new F-Cancer campaign encourages us to have an entirely different kind of awkward conversation with the 'rents... and this time, it's our turn to remind them to be safe.

"One Tree Hill" star Sophia Bush and "Entourage's" Adrian Grenier took part in the campaign by sharing their awkward sex talk experiences -- whether in the first grade or now. Bush talks about her childhood friend Bobby, who got way ahead of himself, and Grenier jokes about his mom's concern for him after seeing Vince's sexcapades on "Entourage."

The point is, if mom and dad were tough enough to fight through the uncomfortableness and educate us, we owe them the same courtesy to remind them about early detection. In addition to Bush and Grenier, the campaign will include the cast of "The Buried Life," Charlie Bewley,  Hosea Chanchez, Deepak Chopra, Fran Drescher, Perez Hilton, Dan Levy, Terrell Owens, Pauley Perrette, Wilmer Valderrama, and Michael Winslow, among others.

You can even go to cancertalk.letsfcancer.com to get Fran Drescher or Michael Winslow to send personalized calls to your parents and relatives encouraging them to chat with you about cancer.